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5j4w

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'''Unreleased structure'''
 
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The entry 5j4w is ON HOLD until Paper Publication
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==DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTGG) in sodium==
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<StructureSection load='5j4w' size='340' side='right'caption='[[5j4w]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5j4w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5J4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5J4W FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5j4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5j4w OCA], [https://pdbe.org/5j4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5j4w RCSB], [https://www.ebi.ac.uk/pdbsum/5j4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5j4w ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The main challenge in DNA quadruplex design is to encode a three-dimensional structure into the primary sequence, despite its multiple, repetitive guanine segments. We identify and detail structural elements describing all 14 feasible canonical quadruplex scaffolds and demonstrate their use in control of design. This work outlines a new roadmap for implementation of targeted design of quadruplexes for material, biotechnological, and therapeutic applications.
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Authors: Dvorkin, S.A., Webba da Silva, M.
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Encoding canonical DNA quadruplex structure.,Dvorkin SA, Karsisiotis AI, Webba da Silva M Sci Adv. 2018 Aug 31;4(8):eaat3007. doi: 10.1126/sciadv.aat3007. eCollection 2018, Aug. PMID:30182059<ref>PMID:30182059</ref>
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Description: DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTGG) in sodium
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Dvorkin, S.A]]
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<div class="pdbe-citations 5j4w" style="background-color:#fffaf0;"></div>
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[[Category: Webba Da Silva, M]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Dvorkin SA]]
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[[Category: Webba da Silva M]]

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DIY G-Quadruplexes: Solution structure of d(GGTTTGGTTTTGGTTGG) in sodium

PDB ID 5j4w

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