5juw

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m (Protected "5juw" [edit=sysop:move=sysop])
Current revision (19:09, 20 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5juw is ON HOLD
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==complex of Dot1l with SS148==
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<StructureSection load='5juw' size='340' side='right'caption='[[5juw]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5juw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JUW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JUW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6NR:(2~{S})-2-AZANYL-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(4-AZANYL-5-CYANO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYLSULFANYL]BUTANOIC+ACID'>6NR</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5juw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5juw OCA], [https://pdbe.org/5juw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5juw RCSB], [https://www.ebi.ac.uk/pdbsum/5juw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5juw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
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Authors: Yu, W., Tempel, W., Li, Y., Spurr, S.S., Bayle, E.D., Fish, P.V., Schapira, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Brown, P.J., Structural Genomics Consortium (SGC)
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==See Also==
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*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]
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Description: complex of Dot1l with SS148
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Bayle, E.D]]
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[[Category: Homo sapiens]]
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[[Category: Li, Y]]
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[[Category: Large Structures]]
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[[Category: Yu, W]]
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[[Category: Arrowsmith CH]]
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[[Category: Schapira, M]]
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[[Category: Bayle ED]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Tempel, W]]
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[[Category: Brown PJ]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Edwards AM]]
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[[Category: Fish, P.V]]
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[[Category: Fish PV]]
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[[Category: Brown, P.J]]
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[[Category: Li Y]]
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[[Category: Edwards, A.M]]
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[[Category: Schapira M]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Spurr SS]]
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[[Category: Spurr, S.S]]
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[[Category: Tempel W]]
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[[Category: Weigelt, J]]
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[[Category: Weigelt J]]
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[[Category: Yu W]]

Current revision

complex of Dot1l with SS148

PDB ID 5juw

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OCA

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