5k4b
From Proteopedia
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(New page: '''Unreleased structure''' The entry 5k4b is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1== | |
| + | <StructureSection load='5k4b' size='340' side='right'caption='[[5k4b]], [[Resolution|resolution]] 1.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5k4b]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nasonia_vitripennis Nasonia vitripennis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K4B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K4B FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.399Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k4b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k4b OCA], [https://pdbe.org/5k4b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k4b RCSB], [https://www.ebi.ac.uk/pdbsum/5k4b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k4b ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EIF3D_NASVI EIF3D_NASVI] mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.[HAMAP-Rule:MF_03003] | ||
| - | + | ==See Also== | |
| - | + | *[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Nasonia vitripennis]] | ||
| + | [[Category: Cate JHD]] | ||
| + | [[Category: Doudna JA]] | ||
| + | [[Category: Kranzusch PJ]] | ||
| + | [[Category: Lee ASY]] | ||
Current revision
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1
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