5k58
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5k58 is ON HOLD Authors: Schumacher, M. Description: Structure of the K. pneumonia SlmA-DNA complex bound to the C-terminal of the cell division pr...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the K. pneumonia SlmA-DNA complex bound to the C-terminal of the cell division protein FtsZ== | |
| - | + | <StructureSection load='5k58' size='340' side='right'caption='[[5k58]], [[Resolution|resolution]] 2.77Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5k58]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O139:H28_str._E24377A Escherichia coli O139:H28 str. E24377A] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K58 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.772Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k58 OCA], [https://pdbe.org/5k58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k58 RCSB], [https://www.ebi.ac.uk/pdbsum/5k58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k58 ProSAT]</span></td></tr> |
| - | [[Category: Schumacher | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SLMA_ECOLI SLMA_ECOLI] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.[HAMAP-Rule:MF_01839]<ref>PMID:15916962</ref> <ref>PMID:21113127</ref> <ref>PMID:21321206</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli O139:H28 str. E24377A]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Schumacher M]] | ||
Current revision
Structure of the K. pneumonia SlmA-DNA complex bound to the C-terminal of the cell division protein FtsZ
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