1ixh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:27, 9 August 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1ixh.gif|left|200px]]
 
-
{{Structure
+
==PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE==
-
|PDB= 1ixh |SIZE=350|CAPTION= <scene name='initialview01'>1ixh</scene>, resolution 0.98&Aring;
+
<StructureSection load='1ixh' size='340' side='right'caption='[[1ixh]], [[Resolution|resolution]] 0.98&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
+
<table><tr><td colspan='2'>[[1ixh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IXH FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.98&#8491;</td></tr>
-
|GENE= PHO-S ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ixh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixh OCA], [https://pdbe.org/1ixh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ixh RCSB], [https://www.ebi.ac.uk/pdbsum/1ixh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ixh ProSAT]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ixh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ixh OCA], [http://www.ebi.ac.uk/pdbsum/1ixh PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ixh RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/PSTS_ECOLI PSTS_ECOLI] Part of the ABC transporter complex PstSACB involved in phosphate import.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/1ixh_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ixh ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
A very short hydrogen bond between an Asp and a phosphate is established in two high resolution structures (0.98 and 1.05 A). A mutant complex that changes the Asp to an Asn, which forms a normal hydrogen bond, has a similar free energy of binding to the wild type complex, suggesting that the contribution of the short hydrogen bond is not extraordinarily strong.
-
'''PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE'''
+
A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.,Wang Z, Luecke H, Yao N, Quiocho FA Nat Struct Biol. 1997 Jul;4(7):519-22. PMID:9228942<ref>PMID:9228942</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 1ixh" style="background-color:#fffaf0;"></div>
-
==Overview==
+
==See Also==
-
A very short hydrogen bond between an Asp and a phosphate is established in two high resolution structures (0.98 and 1.05 A). A mutant complex that changes the Asp to an Asn, which forms a normal hydrogen bond, has a similar free energy of binding to the wild type complex, suggesting that the contribution of the short hydrogen bond is not extraordinarily strong.
+
*[[Phosphate-binding protein|Phosphate-binding protein]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
1IXH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IXH OCA].
+
__TOC__
-
 
+
</StructureSection>
-
==Reference==
+
-
A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes., Wang Z, Luecke H, Yao N, Quiocho FA, Nat Struct Biol. 1997 Jul;4(7):519-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9228942 9228942]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Luecke, H.]]
+
[[Category: Luecke H]]
-
[[Category: Quiocho, F A.]]
+
[[Category: Quiocho FA]]
-
[[Category: Wang, Z.]]
+
[[Category: Wang Z]]
-
[[Category: phosphate bindin protein]]
+
-
[[Category: phosphate transport]]
+
-
[[Category: ultra high resolution]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:26:02 2008''
+

Current revision

PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE

PDB ID 1ixh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ixh"
Personal tools