4zso

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==Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody==
==Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody==
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<StructureSection load='4zso' size='340' side='right' caption='[[4zso]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4zso' size='340' side='right'caption='[[4zso]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4zso]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZSO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4zso]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZSO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zso OCA], [http://pdbe.org/4zso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zso RCSB], [http://www.ebi.ac.uk/pdbsum/4zso PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zso OCA], [https://pdbe.org/4zso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zso RCSB], [https://www.ebi.ac.uk/pdbsum/4zso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zso ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NR3L1_HUMAN NR3L1_HUMAN]] Triggers NCR3-dependent natural killer cell activation.<ref>PMID:19528259</ref>
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[https://www.uniprot.org/uniprot/NR3L1_HUMAN NR3L1_HUMAN] Triggers NCR3-dependent natural killer cell activation.<ref>PMID:19528259</ref>
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of human antibody|3D structures of human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Li, Y]]
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[[Category: Homo sapiens]]
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[[Category: Mariuzza, R A]]
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[[Category: Large Structures]]
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[[Category: Xu, X]]
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[[Category: Li Y]]
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[[Category: Antibody]]
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[[Category: Mariuzza RA]]
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[[Category: Immune system]]
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[[Category: Xu X]]
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[[Category: Tumor ligand b7-h6]]
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Current revision

Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody

PDB ID 4zso

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