1iy9

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[[Image:1iy9.gif|left|200px]]
 
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{{Structure
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==Crystal structure of spermidine synthase==
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|PDB= 1iy9 |SIZE=350|CAPTION= <scene name='initialview01'>1iy9</scene>, resolution 2.30&Aring;
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<StructureSection load='1iy9' size='340' side='right'caption='[[1iy9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1iy9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IY9 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Spermidine_synthase Spermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.16 2.5.1.16] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iy9 OCA], [https://pdbe.org/1iy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iy9 RCSB], [https://www.ebi.ac.uk/pdbsum/1iy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iy9 ProSAT], [https://www.topsan.org/Proteins/NESGC/1iy9 TOPSAN]</span></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00811 PRK00811]</span>
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iy9 OCA], [http://www.ebi.ac.uk/pdbsum/1iy9 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1iy9 RCSB]</span>
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[https://www.uniprot.org/uniprot/SPEE_BACSU SPEE_BACSU] Involved in the cell growth and proliferation. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine (Probable).<ref>PMID:9723923</ref>
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/1iy9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iy9 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of spermidine synthase'''
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==See Also==
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*[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1IY9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IY9 OCA].
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Spermidine synthase]]
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[[Category: Acton T]]
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[[Category: Acton, T.]]
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[[Category: Hunt JF]]
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[[Category: Hunt, J F.]]
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[[Category: Montelione G]]
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[[Category: Montelione, G.]]
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[[Category: Rost B]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Shen J]]
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[[Category: Rost, B.]]
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[[Category: Smith PC]]
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[[Category: Shen, J.]]
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[[Category: Tan AY]]
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[[Category: Smith, P C.]]
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[[Category: Xiao R]]
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[[Category: Tan, A Y.]]
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[[Category: Xiao, R.]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: rossmann fold]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:26:20 2008''
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Current revision

Crystal structure of spermidine synthase

PDB ID 1iy9

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OCA

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