This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5ioe

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:34, 6 October 2017) (edit) (undo)
(Redirecting to 5wo1)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
 
+
#REDIRECT [[5wo1]] This PDB entry is obsolete and replaced by 5wo1
-
==Chaperone Spy H96L bound to Im7 L18A L19A L37A (Im7 un-modeled)==
+
-
<StructureSection load='5ioe' size='340' side='right' caption='[[5ioe]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
+
-
== Structural highlights ==
+
-
<table><tr><td colspan='2'>[[5ioe]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IOE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IOE FirstGlance]. <br>
+
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ina|5ina]], [[5ioa|5ioa]], [[5iog|5iog]]</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ioe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ioe OCA], [http://pdbe.org/5ioe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ioe RCSB], [http://www.ebi.ac.uk/pdbsum/5ioe PDBsum]</span></td></tr>
+
-
</table>
+
-
== Function ==
+
-
[[http://www.uniprot.org/uniprot/SPY_ECOLI SPY_ECOLI]] An ATP-independent periplasmic chaperone, decreases protein aggregation and helps protein refolding. Binds substrate over a large region of its convex inner surface (PubMed:21317898, PubMed:24497545). Substrate protein folds while it is bound to chaperone (PubMed:26619265). Increasing Spy flexibility increases its substrate affinity and overall chaperone activity (shown for 3 different substrates) (PubMed:24497545). Protects proteins in vitro against tannin inactivation; tannins have antimicrobial activity (PubMed:21317898). Overexpression enhances the stability of otherwise unstable periplasmic proteins (PubMed:21317898).<ref>PMID:21317898</ref> <ref>PMID:24497545</ref> <ref>PMID:26619265</ref>
+
-
== References ==
+
-
<references/>
+
-
__TOC__
+
-
</StructureSection>
+
-
[[Category: Bardwell, J C.A]]
+
-
[[Category: Horowitz, S]]
+
-
[[Category: Koldewey, P]]
+
-
[[Category: Martin, R]]
+
-
[[Category: Chaperone]]
+

Current revision

  1. REDIRECT 5wo1 This PDB entry is obsolete and replaced by 5wo1

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5ioe"
Personal tools