5b5q
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==1.7 Angstroms structure of ChlaDub1 from Chlamydia Trachomatis== | |
| - | + | <StructureSection load='5b5q' size='340' side='right'caption='[[5b5q]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5b5q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydia_trachomatis Chlamydia trachomatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B5Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B5Q FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b5q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b5q OCA], [https://pdbe.org/5b5q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b5q RCSB], [https://www.ebi.ac.uk/pdbsum/5b5q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b5q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CDUB1_CHLT2 CDUB1_CHLT2] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protease possesses deubiquitinating and deneddylating activities (By similarity). Impairs ubiquitination and degradation of NF-kappa-B inhibitor alpha (NFKBIA), thereby preventing NF-kappa-B activation.<ref>PMID:18503636</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chlamydia trachomatis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Kisker C]] | ||
| + | [[Category: Ramirez YA]] | ||
| + | [[Category: Sauer F]] | ||
Current revision
1.7 Angstroms structure of ChlaDub1 from Chlamydia Trachomatis
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