5b6q
From Proteopedia
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(New page: '''Unreleased structure''' The entry 5b6q is ON HOLD Authors: Description: Category: Unreleased Structures) |
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of monomeric cytochrome c5 from Shewanella violacea== | |
+ | <StructureSection load='5b6q' size='340' side='right'caption='[[5b6q]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5b6q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_violacea Shewanella violacea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B6Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B6Q FirstGlance]. <br> | ||
+ | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b6q OCA], [https://pdbe.org/5b6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b6q RCSB], [https://www.ebi.ac.uk/pdbsum/5b6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b6q ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/D4ZE39_SHEVD D4ZE39_SHEVD] | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | Monomeric cytochrome c5 from deep-sea piezophilic Shewanella violacea (SVcytc5) was stable against heat and denaturant compared with the homologous protein from shallow-sea piezo-sensitive Shewanella livingstonensis (SLcytc5). Here, the SVcytc5 crystal structure revealed that the Lys-50 side chain on the flexible loop formed a hydrogen bond with heme whereas that of corresponding hydrophobic Leu-50 could not form such a bond in SLcytc5, which appeared to be one of possible factors responsible for the difference in stability between the two proteins. This structural insight was confirmed by a reciprocal mutagenesis study on the thermal stability of these two proteins. As SVcytc5 was isolated from a deep-sea piezophilic bacterium, the present comparative study indicates that adaptation of monomeric SVcytc5 to high pressure environments results in stabilization against heat. | ||
- | + | Comparative study on stabilization mechanism of monomeric cytochrome c5 from deep-sea piezophilic Shewanella violacea.,Masanari M, Fujii S, Kawahara K, Oki H, Tsujino H, Maruno T, Kobayashi Y, Ohkubo T, Wakai S, Sambongi Y Biosci Biotechnol Biochem. 2016 Dec;80(12):2365-2370. Epub 2016 Sep 20. PMID:27648635<ref>PMID:27648635</ref> | |
- | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
- | [[Category: | + | </div> |
+ | <div class="pdbe-citations 5b6q" style="background-color:#fffaf0;"></div> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Shewanella violacea]] | ||
+ | [[Category: Fujii S]] | ||
+ | [[Category: Harada Y]] | ||
+ | [[Category: Kawahara K]] | ||
+ | [[Category: Kobayashi Y]] | ||
+ | [[Category: Maruno T]] | ||
+ | [[Category: Masanari M]] | ||
+ | [[Category: Nishiyama M]] | ||
+ | [[Category: Ohkubo T]] | ||
+ | [[Category: Oki H]] | ||
+ | [[Category: Sambongi Y]] | ||
+ | [[Category: Tsujino H]] | ||
+ | [[Category: Wakai S]] |
Current revision
Crystal structure of monomeric cytochrome c5 from Shewanella violacea
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Categories: Large Structures | Shewanella violacea | Fujii S | Harada Y | Kawahara K | Kobayashi Y | Maruno T | Masanari M | Nishiyama M | Ohkubo T | Oki H | Sambongi Y | Tsujino H | Wakai S