5l4x
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of FimH lectin domain in complex with 4-Deoxy-Heptylmannoside== | |
| + | <StructureSection load='5l4x' size='340' side='right'caption='[[5l4x]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5l4x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L4X FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6KU:heptyl+4-deoxy-4-deoxy-alpha-D-mannopyranoside'>6KU</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l4x OCA], [https://pdbe.org/5l4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l4x RCSB], [https://www.ebi.ac.uk/pdbsum/5l4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l4x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | ||
| - | + | ==See Also== | |
| - | + | *[[Adhesin 3D structures|Adhesin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ernst B]] | ||
| + | [[Category: Jakob RP]] | ||
| + | [[Category: Maier T]] | ||
| + | [[Category: Rabbani S]] | ||
| + | [[Category: Zihlmann P]] | ||
Current revision
Crystal structure of FimH lectin domain in complex with 4-Deoxy-Heptylmannoside
| |||||||||||
