5l6x
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5l6x is ON HOLD Authors: Lopez-Jaramillo, F.J., Garcia-Fuentes, L.., Vargas-Berenguel, A. Description: CRYSTAL STRUCTURE OF HGSTP1-1 COMPLEXED WITH...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==CRYSTAL STRUCTURE OF HGSTP1-1 COMPLEXED WITH FERROCENE-GLUTATHIONE CONJUGATE== | |
| + | <StructureSection load='5l6x' size='340' side='right'caption='[[5l6x]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5l6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L6X FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6SG:S-[N-(ferrocenylmethyl)carbamoylmethyl]-glutathione'>6SG</scene>, <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l6x OCA], [https://pdbe.org/5l6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l6x RCSB], [https://www.ebi.ac.uk/pdbsum/5l6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l6x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GSTP1_HUMAN GSTP1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.<ref>PMID:21668448</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Garcia-Fuentes | + | __TOC__ |
| - | [[Category: Lopez-Jaramillo | + | </StructureSection> |
| - | [[Category: Vargas-Berenguel | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Garcia-Fuentes L]] | ||
| + | [[Category: Lopez-Jaramillo FJ]] | ||
| + | [[Category: Vargas-Berenguel A]] | ||
Current revision
CRYSTAL STRUCTURE OF HGSTP1-1 COMPLEXED WITH FERROCENE-GLUTATHIONE CONJUGATE
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