5l7r
From Proteopedia
(Difference between revisions)
m (Protected "5l7r" [edit=sysop:move=sysop]) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of BvGH123== | |
| + | <StructureSection load='5l7r' size='340' side='right'caption='[[5l7r]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5l7r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Phocaeicola_vulgatus_ATCC_8482 Phocaeicola vulgatus ATCC 8482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L7R FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l7r OCA], [https://pdbe.org/5l7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l7r RCSB], [https://www.ebi.ac.uk/pdbsum/5l7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l7r ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A6L2E5_PHOV8 A6L2E5_PHOV8] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Bacteroides vulgatus is a member of the human microbiota whose abundance is increased in patients with Crohn's disease. We show that a B. vulgatus glycoside hydrolase from the carbohydrate active enzyme family GH123, BvGH123, is an N-acetyl-beta-galactosaminidase that acts with retention of stereochemistry, and, through a 3-D structure in complex with Gal-thiazoline, provide evidence in support of a neighbouring group participation mechanism. | ||
| - | + | Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-beta-galactosaminidase that uses neighbouring group participation.,Roth C, Petricevic M, John A, Goddard-Borger ED, Davies GJ, Williams SJ Chem Commun (Camb). 2016 Sep 25;52(74):11096-9. doi: 10.1039/c6cc04649e. Epub, 2016 Aug 22. PMID:27546776<ref>PMID:27546776</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 5l7r" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Phocaeicola vulgatus ATCC 8482]] | ||
| + | [[Category: Davies GJ]] | ||
| + | [[Category: Goddard-Borger ED]] | ||
| + | [[Category: John A]] | ||
| + | [[Category: Petricevic M]] | ||
| + | [[Category: Roth C]] | ||
| + | [[Category: Williams SJ]] | ||
Current revision
Crystal structure of BvGH123
| |||||||||||
