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5hxr

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==Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 10mM Ca2+==
==Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 10mM Ca2+==
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<StructureSection load='5hxr' size='340' side='right' caption='[[5hxr]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
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<StructureSection load='5hxr' size='340' side='right'caption='[[5hxr]], [[Resolution|resolution]] 2.46&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hxr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HXR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hxr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HXR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.463&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hya|5hya]], [[5hxs|5hxs]], [[5hxh|5hxh]], [[5hxe|5hxe]], [[5hxc|5hxc]], [[5hwy|5hwy]], [[5hwx|5hwx]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxr OCA], [http://pdbe.org/5hxr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hxr RCSB], [http://www.ebi.ac.uk/pdbsum/5hxr PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hxr OCA], [https://pdbe.org/5hxr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hxr RCSB], [https://www.ebi.ac.uk/pdbsum/5hxr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hxr ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Y091_METJA Y091_METJA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Faraldo-Gomez, J D]]
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[[Category: Large Structures]]
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[[Category: Jiang, Y X]]
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[[Category: Methanocaldococcus jannaschii DSM 2661]]
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[[Category: Liao, J]]
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[[Category: Faraldo-Gomez JD]]
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[[Category: Calcium signalling]]
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[[Category: Jiang YX]]
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[[Category: Induced conformational change]]
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[[Category: Liao J]]
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[[Category: Membrane protein]]
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[[Category: Membrane transporter]]
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[[Category: Na+/ca2+ exchange]]
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Current revision

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 10mM Ca2+

PDB ID 5hxr

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