5kg8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Rigor myosin X co-complexed with an actin filament== | |
| + | <SX load='5kg8' size='340' side='right' viewer='molstar' caption='[[5kg8]], [[Resolution|resolution]] 9.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5kg8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KG8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KG8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.1Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kg8 OCA], [https://pdbe.org/5kg8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kg8 RCSB], [https://www.ebi.ac.uk/pdbsum/5kg8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kg8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MYO10_HUMAN MYO10_HUMAN] Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podosome belt in osteoclasts (By similarity).<ref>PMID:16894163</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Actin 3D structures|Actin 3D structures]] | |
| - | + | *[[Myosin 3D Structures|Myosin 3D Structures]] | |
| - | [[Category: | + | == References == |
| - | [[Category: Houdusse | + | <references/> |
| - | [[Category: Sindelar | + | __TOC__ |
| - | [[Category: Sweeney | + | </SX> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Houdusse A]] | ||
| + | [[Category: Sindelar CV]] | ||
| + | [[Category: Sweeney L]] | ||
Current revision
Rigor myosin X co-complexed with an actin filament
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