5lba

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(New page: '''Unreleased structure''' The entry 5lba is ON HOLD Authors: Newman, J.A., Aitkenhead, H., Talon, R., Savitsky, P., Krojer, T., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra,...)
Current revision (16:13, 4 October 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5lba is ON HOLD
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==Crystal structure of human RECQL5 helicase in complex with DSPL fragment(1-cyclohexyl-3-(oxolan-2-ylmethyl)urea, SGC - Diamond XChem I04-1 fragment screening.==
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<StructureSection load='5lba' size='340' side='right'caption='[[5lba]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5lba]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LBA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6SV:1-CYCLOHEXYL-3-[[(2~{R})-OXOLAN-2-YL]METHYL]UREA'>6SV</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lba OCA], [https://pdbe.org/5lba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lba RCSB], [https://www.ebi.ac.uk/pdbsum/5lba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lba ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RECQ5_HUMAN RECQ5_HUMAN] May have an important role in DNA metabolism.
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Authors: Newman, J.A., Aitkenhead, H., Talon, R., Savitsky, P., Krojer, T., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Gileadi, O., Structural Genomics Consortium (SGC)
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==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
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Description: Crystal structure of human RECQL5 helicase in complex with 3D fragment (1-cyclohexyl-3-(oxolan-2-ylmethyl)urea)
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Aitkenhead, H]]
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[[Category: Homo sapiens]]
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[[Category: Krojer, T]]
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[[Category: Large Structures]]
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[[Category: Bountra, C]]
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[[Category: Aitkenhead H]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Arrowsmith CH]]
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[[Category: Von Delft, F]]
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[[Category: Bountra C]]
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[[Category: Edwards, A.M]]
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[[Category: Edwards AM]]
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[[Category: Talon, R]]
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[[Category: Gileadi O]]
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[[Category: Gileadi, O]]
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[[Category: Krojer T]]
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[[Category: Newman, J.A]]
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[[Category: Newman JA]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Savitsky P]]
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[[Category: Savitsky, P]]
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[[Category: Talon R]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of human RECQL5 helicase in complex with DSPL fragment(1-cyclohexyl-3-(oxolan-2-ylmethyl)urea, SGC - Diamond XChem I04-1 fragment screening.

PDB ID 5lba

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OCA

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