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5ery

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==Crystal Structure of APO MenD from M. tuberculosis - P212121==
==Crystal Structure of APO MenD from M. tuberculosis - P212121==
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<StructureSection load='5ery' size='340' side='right' caption='[[5ery]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='5ery' size='340' side='right'caption='[[5ery]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ery]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ERY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ERY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ery]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ERY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ERY FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5erx|5erx]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid_synthase 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.9 2.2.1.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ery FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ery OCA], [https://pdbe.org/5ery PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ery RCSB], [https://www.ebi.ac.uk/pdbsum/5ery PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ery ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ery FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ery OCA], [http://pdbe.org/5ery PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ery RCSB], [http://www.ebi.ac.uk/pdbsum/5ery PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MEND_MYCTU MEND_MYCTU]] Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
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[https://www.uniprot.org/uniprot/MEND_MYCTU MEND_MYCTU] Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase]]
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[[Category: Large Structures]]
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[[Category: Baker, E N]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Bashiri, G]]
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[[Category: Baker EN]]
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[[Category: Bulloch, E M.M]]
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[[Category: Bashiri G]]
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[[Category: Jirgis, E N.M]]
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[[Category: Bulloch EMM]]
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[[Category: Johnston, J M]]
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[[Category: Jirgis ENM]]
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[[Category: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase]]
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[[Category: Johnston JM]]
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[[Category: Menaquinone biosynthesis]]
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[[Category: Mend]]
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[[Category: Pyruvate oxidase family]]
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[[Category: Thiamin-diphosphate dependent enzyme]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of APO MenD from M. tuberculosis - P212121

PDB ID 5ery

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