5fdp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:47, 19 July 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.==
==Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.==
-
<StructureSection load='5fdp' size='340' side='right' caption='[[5fdp]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
+
<StructureSection load='5fdp' size='340' side='right'caption='[[5fdp]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5fdp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5fdp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FDP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5WR:(4~{S})-4-METHYL-~{N}-[3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-5-(TRIFLUOROMETHYL)PHENYL]-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLINE-7-CARBOXAMIDE'>5WR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5WR:(4~{S})-4-METHYL-~{N}-[3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-5-(TRIFLUOROMETHYL)PHENYL]-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLINE-7-CARBOXAMIDE'>5WR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdp OCA], [http://pdbe.org/5fdp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdp RCSB], [http://www.ebi.ac.uk/pdbsum/5fdp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdp ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdp OCA], [https://pdbe.org/5fdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fdp RCSB], [https://www.ebi.ac.uk/pdbsum/5fdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdp ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DDR1_HUMAN DDR1_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 19:
</div>
</div>
<div class="pdbe-citations 5fdp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5fdp" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Epithelial discoidin domain-containing receptor|Epithelial discoidin domain-containing receptor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Receptor protein-tyrosine kinase]]
+
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Large Structures]]
-
[[Category: Bartual, S G]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Borkowska, O]]
+
[[Category: Bartual SG]]
-
[[Category: Bountra, C]]
+
[[Category: Borkowska O]]
-
[[Category: Bullock, A]]
+
[[Category: Bountra C]]
-
[[Category: Burgess-Brown, N]]
+
[[Category: Bullock A]]
-
[[Category: Chaikuad, A]]
+
[[Category: Burgess-Brown N]]
-
[[Category: Delft, F Von]]
+
[[Category: Chaikuad A]]
-
[[Category: Ding, K]]
+
[[Category: Ding K]]
-
[[Category: Edwards, A M]]
+
[[Category: Edwards AM]]
-
[[Category: Kopec, J]]
+
[[Category: Kopec J]]
-
[[Category: Kupinska, K]]
+
[[Category: Kupinska K]]
-
[[Category: Mahajan, P]]
+
[[Category: Mahajan P]]
-
[[Category: Mukhopadhyay, S]]
+
[[Category: Mukhopadhyay S]]
-
[[Category: Newman, J]]
+
[[Category: Newman J]]
-
[[Category: Pinkas, D M]]
+
[[Category: Pinkas DM]]
-
[[Category: Structural genomic]]
+
[[Category: Sorell F]]
-
[[Category: Sorell, F]]
+
[[Category: Strain-Damerell C]]
-
[[Category: Strain-Damerell, C]]
+
[[Category: Tallant C]]
-
[[Category: Tallant, C]]
+
[[Category: Talon R]]
-
[[Category: Talon, R]]
+
[[Category: Wang Z]]
-
[[Category: Wang, Z]]
+
[[Category: Williams E]]
-
[[Category: Williams, E]]
+
[[Category: Von Delft F]]
-
[[Category: Ddr1 kinase]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Psi-biology]]
+
-
[[Category: Sgc]]
+
-
[[Category: Transferase]]
+

Current revision

Structure of DDR1 receptor tyrosine kinase in complex with D2099 inhibitor at 2.25 Angstroms resolution.

PDB ID 5fdp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5fdp"
Personal tools