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4ybu

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==Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human Cellular Retinoic Acid Binding ProteinII in complex with Retinal after 24 h incubation and 1 hour UV irradiation at 1.92 angstrom - 1st cycle==
==Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human Cellular Retinoic Acid Binding ProteinII in complex with Retinal after 24 h incubation and 1 hour UV irradiation at 1.92 angstrom - 1st cycle==
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<StructureSection load='4ybu' size='340' side='right' caption='[[4ybu]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
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<StructureSection load='4ybu' size='340' side='right'caption='[[4ybu]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ybu]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YBU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YBU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ybu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YBU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.924&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ybp|4ybp]], [[2g7b|2g7b]], [[4i9r|4i9r]], [[4i9s|4i9s]], [[4ruu|4ruu]], [[4eej|4eej]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ybu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ybu OCA], [http://pdbe.org/4ybu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ybu RCSB], [http://www.ebi.ac.uk/pdbsum/4ybu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ybu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ybu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ybu OCA], [https://pdbe.org/4ybu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ybu RCSB], [https://www.ebi.ac.uk/pdbsum/4ybu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ybu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN]] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
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[https://www.uniprot.org/uniprot/RABP2_HUMAN RABP2_HUMAN] Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4ybu" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4ybu" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cellular retinoic acid-binding protein 3D structures|Cellular retinoic acid-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Geiger, J H]]
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[[Category: Homo sapiens]]
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[[Category: Nosrati, M]]
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[[Category: Large Structures]]
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[[Category: Photoswitchable protein]]
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[[Category: Geiger JH]]
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[[Category: Protein engineering]]
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[[Category: Nosrati M]]
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[[Category: Retinal iminium pka change by isomerization]]
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[[Category: Retinal isomerization]]
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[[Category: Retinal psb]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human Cellular Retinoic Acid Binding ProteinII in complex with Retinal after 24 h incubation and 1 hour UV irradiation at 1.92 angstrom - 1st cycle

PDB ID 4ybu

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