1jlx

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[[Image:1jlx.gif|left|200px]]
 
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{{Structure
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==AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE==
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|PDB= 1jlx |SIZE=350|CAPTION= <scene name='initialview01'>1jlx</scene>, resolution 2.2&Aring;
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<StructureSection load='1jlx' size='340' side='right'caption='[[1jlx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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|SITE= <scene name='pdbsite=S1:Carbohydrate+Binding+Site'>S1</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MBN:TOLUENE'>MBN</scene>
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<table><tr><td colspan='2'>[[1jlx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Amaranthus_caudatus Amaranthus caudatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JLX FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FOR:FORMYL+GROUP'>FOR</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MBN:TOLUENE'>MBN</scene>, <scene name='pdbligand=PRD_900084:Thomsen-Friedenreich+antigen'>PRD_900084</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jlx OCA], [https://pdbe.org/1jlx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jlx RCSB], [https://www.ebi.ac.uk/pdbsum/1jlx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jlx ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jlx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jlx OCA], [http://www.ebi.ac.uk/pdbsum/1jlx PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1jlx RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Q71QF2_AMACA Q71QF2_AMACA]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Amaranthus caudatus agglutinin contains a novel arrangement of four beta-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when 'masked' by other sugars.
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'''AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE'''
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Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.,Transue TR, Smith AK, Mo H, Goldstein IJ, Saper MA Nat Struct Biol. 1997 Oct;4(10):779-83. PMID:9334739<ref>PMID:9334739</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1jlx" style="background-color:#fffaf0;"></div>
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==Overview==
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==See Also==
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Amaranthus caudatus agglutinin contains a novel arrangement of four beta-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when 'masked' by other sugars.
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1JLX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Amaranthus_caudatus Amaranthus caudatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JLX OCA].
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__TOC__
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</StructureSection>
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==Reference==
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Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin., Transue TR, Smith AK, Mo H, Goldstein IJ, Saper MA, Nat Struct Biol. 1997 Oct;4(10):779-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9334739 9334739]
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[[Category: Amaranthus caudatus]]
[[Category: Amaranthus caudatus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Goldstein, I J.]]
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[[Category: Goldstein IJ]]
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[[Category: Mo, H.]]
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[[Category: Mo H]]
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[[Category: Saper, M A.]]
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[[Category: Saper MA]]
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[[Category: Smith, A K.]]
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[[Category: Smith AK]]
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[[Category: Transue, T R.]]
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[[Category: Transue TR]]
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[[Category: bivalent]]
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[[Category: complex (lectin/saccharide)]]
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[[Category: lectin]]
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[[Category: t-disaccharide homodimer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:35:36 2008''
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Current revision

AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE

PDB ID 1jlx

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