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5c59

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==Crystal structure of the periplasmic region of MacB from E. coli==
==Crystal structure of the periplasmic region of MacB from E. coli==
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<StructureSection load='5c59' size='340' side='right' caption='[[5c59]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='5c59' size='340' side='right'caption='[[5c59]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5c59]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C59 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C59 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5c59]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_536 Escherichia coli 536]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C59 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c59 OCA], [http://pdbe.org/5c59 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c59 RCSB], [http://www.ebi.ac.uk/pdbsum/5c59 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c59 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c59 OCA], [https://pdbe.org/5c59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c59 RCSB], [https://www.ebi.ac.uk/pdbsum/5c59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c59 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MACB_ECOL5 MACB_ECOL5]] Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
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[https://www.uniprot.org/uniprot/MACB_ECOL5 MACB_ECOL5] Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ha, N C]]
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[[Category: Escherichia coli 536]]
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[[Category: Kim, J S]]
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[[Category: Large Structures]]
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[[Category: Abc transporter]]
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[[Category: Ha NC]]
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[[Category: Efflux pump]]
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[[Category: Kim JS]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of the periplasmic region of MacB from E. coli

PDB ID 5c59

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