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5d48
From Proteopedia
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==Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid== | ==Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid== | ||
| - | <StructureSection load='5d48' size='340' side='right' caption='[[5d48]], [[Resolution|resolution]] 1.81Å' scene=''> | + | <StructureSection load='5d48' size='340' side='right'caption='[[5d48]], [[Resolution|resolution]] 1.81Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5d48]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D48 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5d48]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D48 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L96:3-{5-CYCLOPROPYL-3-(3,5-DIMETHYL-1H-PYRAZOL-4-YL)-2-[3-(PROPAN-2-YLOXY)PHENYL]-1H-INDOL-1-YL}PROPANOIC+ACID'>L96</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L96:3-{5-CYCLOPROPYL-3-(3,5-DIMETHYL-1H-PYRAZOL-4-YL)-2-[3-(PROPAN-2-YLOXY)PHENYL]-1H-INDOL-1-YL}PROPANOIC+ACID'>L96</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d48 OCA], [https://pdbe.org/5d48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d48 RCSB], [https://www.ebi.ac.uk/pdbsum/5d48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d48 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5d48" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5d48" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Ejima | + | [[Category: Homo sapiens]] |
| - | [[Category: Hatanaka | + | [[Category: Large Structures]] |
| - | [[Category: Igarashi | + | [[Category: Ejima C]] |
| - | [[Category: Ishikawa | + | [[Category: Hatanaka T]] |
| - | [[Category: Kashiwagi | + | [[Category: Igarashi S]] |
| - | [[Category: Miyanaga | + | [[Category: Ishikawa K]] |
| - | [[Category: Miyano | + | [[Category: Kashiwagi T]] |
| - | [[Category: Mizukoshi | + | [[Category: Miyanaga W]] |
| - | [[Category: Sugiki | + | [[Category: Miyano H]] |
| - | [[Category: Tagami | + | [[Category: Mizukoshi T]] |
| - | [[Category: Takahashi | + | [[Category: Sugiki M]] |
| - | [[Category: Takeshita | + | [[Category: Tagami U]] |
| - | [[Category: Tokumasu | + | [[Category: Takahashi K]] |
| - | [[Category: Yoshida | + | [[Category: Takeshita S]] |
| - | + | [[Category: Tokumasu M]] | |
| - | + | [[Category: Yoshida T]] | |
Current revision
Crystal Structure of FABP4 in complex with 3-{5-cyclopropyl-3-(3,5-dimethyl-1H-pyrazol-4-yl)-2-[3-(propan-2-yloxy) phenyl]-1H-indol-1-yl}propanoic acid
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Categories: Homo sapiens | Large Structures | Ejima C | Hatanaka T | Igarashi S | Ishikawa K | Kashiwagi T | Miyanaga W | Miyano H | Mizukoshi T | Sugiki M | Tagami U | Takahashi K | Takeshita S | Tokumasu M | Yoshida T
