5etv

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==S. aureus 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.72 angstrom resolution==
==S. aureus 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.72 angstrom resolution==
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<StructureSection load='5etv' size='340' side='right' caption='[[5etv]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
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<StructureSection load='5etv' size='340' side='right'caption='[[5etv]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5etv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ETV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ETV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5etv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ETV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ETV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5RZ:2-AZANYL-8-[2-(4-BROMOPHENYL)-2-OXIDANYLIDENE-ETHYL]SULFANYL-1,9-DIHYDROPURIN-6-ONE'>5RZ</scene>, <scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5RZ:2-AZANYL-8-[2-(4-BROMOPHENYL)-2-OXIDANYLIDENE-ETHYL]SULFANYL-1,9-DIHYDROPURIN-6-ONE'>5RZ</scene>, <scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5etp|5etp]], [[5etk|5etk]], [[5etl|5etl]], [[5etm|5etm]], [[5etn|5etn]], [[5eto|5eto]], [[5etq|5etq]], [[5etr|5etr]], [[5ets|5ets]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5etv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5etv OCA], [https://pdbe.org/5etv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5etv RCSB], [https://www.ebi.ac.uk/pdbsum/5etv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5etv ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-amino-4-hydroxy-6-hydroxymethyldihydropteridine_diphosphokinase 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.3 2.7.6.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5etv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5etv OCA], [http://pdbe.org/5etv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5etv RCSB], [http://www.ebi.ac.uk/pdbsum/5etv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5etv ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q2G0Q5_STAA8 Q2G0Q5_STAA8]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5etv" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5etv" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[HPPK 3D structures|HPPK 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
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[[Category: Large Structures]]
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[[Category: Dennis, M L]]
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[[Category: Staphylococcus aureus]]
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[[Category: Peat, T S]]
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[[Category: Dennis ML]]
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[[Category: Swarbrick, J D]]
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[[Category: Peat TS]]
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[[Category: Ampcpp]]
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[[Category: Swarbrick JD]]
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[[Category: Complex]]
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[[Category: Inhibitor]]
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[[Category: Pyrophosphokinase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

S. aureus 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase complexed with AMPCPP and inhibitor at 1.72 angstrom resolution

PDB ID 5etv

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