5jmv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:58, 20 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of mjKae1-pfuPcc1 complex==
==Crystal structure of mjKae1-pfuPcc1 complex==
-
<StructureSection load='5jmv' size='340' side='right' caption='[[5jmv]], [[Resolution|resolution]] 3.39&Aring;' scene=''>
+
<StructureSection load='5jmv' size='340' side='right'caption='[[5jmv]], [[Resolution|resolution]] 3.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5jmv]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JMV FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5jmv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661] and [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JMV FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3864696&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jmv OCA], [http://pdbe.org/5jmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jmv RCSB], [http://www.ebi.ac.uk/pdbsum/5jmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jmv ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jmv OCA], [https://pdbe.org/5jmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jmv RCSB], [https://www.ebi.ac.uk/pdbsum/5jmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jmv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/KAE1B_METJA KAE1B_METJA]] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does not have endonuclease activity.[HAMAP-Rule:MF_01447]<ref>PMID:18951093</ref>
+
[https://www.uniprot.org/uniprot/KAE1B_METJA KAE1B_METJA] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction (By similarity). The Bud32 domain probably displays kinase activity that regulates Kae1 function. In vitro, exhibits low ATPase activity, but does not bind DNA and does not have endonuclease activity.[HAMAP-Rule:MF_01447]<ref>PMID:18951093</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Sicheri, F]]
+
[[Category: Large Structures]]
-
[[Category: Wan, L]]
+
[[Category: Methanocaldococcus jannaschii DSM 2661]]
-
[[Category: Transferase]]
+
[[Category: Pyrococcus furiosus DSM 3638]]
-
[[Category: Trna modification]]
+
[[Category: Sicheri F]]
 +
[[Category: Wan L]]

Current revision

Crystal structure of mjKae1-pfuPcc1 complex

PDB ID 5jmv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5jmv"
Personal tools