5ipo
From Proteopedia
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==Solution Structure of Hge36: Scorpine-like Peptide from Hadrurus Gertschi== | ==Solution Structure of Hge36: Scorpine-like Peptide from Hadrurus Gertschi== | ||
| - | <StructureSection load='5ipo' size='340' side='right' caption='[[5ipo | + | <StructureSection load='5ipo' size='340' side='right'caption='[[5ipo]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ipo]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPO OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5ipo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hadrurus_gertschi Hadrurus gertschi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IPO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IPO FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ipo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ipo OCA], [https://pdbe.org/5ipo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ipo RCSB], [https://www.ebi.ac.uk/pdbsum/5ipo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ipo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/KBX3_HADGE KBX3_HADGE]] Hge-scorpine has antibacterial activity against B.subtilis, but not against S.aureus. Also has hemolytic and cytolytic activities.<ref>PMID:18030427</ref> Hge36 peptide blocks Kv1.1/KCNA1 (IC(50)=185 nM) potassium channels. Shows a weak hemolytic activity.<ref>PMID:18030427</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Flores-Solis, D]] | ||
| - | [[Category: Rio-Portilla, F del]] | ||
| - | [[Category: Vega, R Rodriguez De La]] | ||
| - | [[Category: Antiparasitic activity]] | ||
[[Category: Hadrurus gertschi]] | [[Category: Hadrurus gertschi]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Flores-Solis D]] |
| + | [[Category: Rodriguez De La Vega R]] | ||
| + | [[Category: Del Rio-Portilla F]] | ||
Current revision
Solution Structure of Hge36: Scorpine-like Peptide from Hadrurus Gertschi
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