1k47

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[[Image:1k47.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)==
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|PDB= 1k47 |SIZE=350|CAPTION= <scene name='initialview01'>1k47</scene>, resolution 2.42&Aring;
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<StructureSection load='1k47' size='340' side='right'caption='[[1k47]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1k47]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K47 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphomevalonate_kinase Phosphomevalonate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.2 2.7.4.2] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
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|GENE= mvaK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 Streptococcus pneumoniae])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1577 ERG12]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k47 OCA], [https://pdbe.org/1k47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k47 RCSB], [https://www.ebi.ac.uk/pdbsum/1k47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k47 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1k47 TOPSAN]</span></td></tr>
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|RELATEDENTRY=[[1fi4|1FI4]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k47 OCA], [http://www.ebi.ac.uk/pdbsum/1k47 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1k47 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/Q8DR49_STRR6 Q8DR49_STRR6]
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== Evolutionary Conservation ==
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'''Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/1k47_consurf.spt"</scriptWhenChecked>
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1K47 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K47 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Crystal structure of the Streptococcus pneumoniae phosphomevalonate kinase, a member of the GHMP kinase superfamily., Romanowski MJ, Bonanno JB, Burley SK, Proteins. 2002 Jun 1;47(4):568-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12001237 12001237]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k47 ConSurf].
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[[Category: Phosphomevalonate kinase]]
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<div style="clear:both"></div>
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[[Category: Single protein]]
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__TOC__
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[[Category: Streptococcus pneumoniae]]
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</StructureSection>
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[[Category: Bonanno, J B.]]
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[[Category: Large Structures]]
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[[Category: Burley, S K.]]
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[[Category: Streptococcus pneumoniae R6]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Bonanno JB]]
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[[Category: Romanowski, M J.]]
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[[Category: Burley SK]]
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[[Category: alpha/beta single domain belonging to the ghmp kinase superfamily]]
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[[Category: Romanowski MJ]]
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[[Category: mvak2]]
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[[Category: new york structural genomix research consortium]]
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[[Category: nysgxrc]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:43:11 2008''
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Current revision

Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)

PDB ID 1k47

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