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1k4f

From Proteopedia

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[[Image:1k4f.jpg|left|200px]]
 
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{{Structure
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==CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.6 A RESOLUTION==
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|PDB= 1k4f |SIZE=350|CAPTION= <scene name='initialview01'>1k4f</scene>, resolution 1.60&Aring;
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<StructureSection load='1k4f' size='340' side='right'caption='[[1k4f]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1k4f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K4F FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= plasmid pMON234 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k4f OCA], [https://pdbe.org/1k4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k4f RCSB], [https://www.ebi.ac.uk/pdbsum/1k4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k4f ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1fof|1FOF]], [[1e4d|1E4D]], [[1k4e|1K4E]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k4f OCA], [http://www.ebi.ac.uk/pdbsum/1k4f PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1k4f RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/BLO10_PSEAI BLO10_PSEAI] Hydrolyzes both carbenicillin and oxacillin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/1k4f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k4f ConSurf].
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<div style="clear:both"></div>
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'''CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.6 A RESOLUTION'''
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1K4F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K4F OCA].
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[[Category: Large Structures]]
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[[Category: Beta-lactamase]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Single protein]]
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[[Category: Bouillene F]]
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[[Category: Bouillene, F.]]
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[[Category: Charlier P]]
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[[Category: Charlier, P.]]
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[[Category: Fonze E]]
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[[Category: Fonze, E.]]
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[[Category: Frere JM]]
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[[Category: Frere, J M.]]
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[[Category: Kerff F]]
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[[Category: Kerff, F.]]
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[[Category: beta-lactamase]]
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[[Category: carbamylated lysine]]
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[[Category: class d]]
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[[Category: hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:43:16 2008''
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Current revision

CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 AT 1.6 A RESOLUTION

PDB ID 1k4f

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