5aq1

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==Trypanosoma cruzi Glucose-6-phosphate Dehydrogenase in complex with G6P and NADPH==
==Trypanosoma cruzi Glucose-6-phosphate Dehydrogenase in complex with G6P and NADPH==
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<StructureSection load='5aq1' size='340' side='right' caption='[[5aq1]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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<StructureSection load='5aq1' size='340' side='right'caption='[[5aq1]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5aq1]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AQ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AQ1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5aq1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AQ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AQ1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BG6:BETA-D-GLUCOSE-6-PHOSPHATE'>BG6</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_dehydrogenase Glucose-6-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.49 1.1.1.49] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BG6:BETA-D-GLUCOSE-6-PHOSPHATE'>BG6</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aq1 OCA], [http://pdbe.org/5aq1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aq1 RCSB], [http://www.ebi.ac.uk/pdbsum/5aq1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5aq1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aq1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aq1 OCA], [https://pdbe.org/5aq1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aq1 RCSB], [https://www.ebi.ac.uk/pdbsum/5aq1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aq1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q4E0B2_TRYCC Q4E0B2_TRYCC]] Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.[RuleBase:RU362120]
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[https://www.uniprot.org/uniprot/Q4E0B2_TRYCC Q4E0B2_TRYCC] Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.[RuleBase:RU362120]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5aq1" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5aq1" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Glucose 6-phosphate dehydrogenase|Glucose 6-phosphate dehydrogenase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glucose-6-phosphate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Cordeiro, A T]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Dawson, A]]
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[[Category: Cordeiro AT]]
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[[Category: Hunter, W N]]
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[[Category: Dawson A]]
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[[Category: Mercaldi, G F]]
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[[Category: Hunter WN]]
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[[Category: Chagas disease]]
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[[Category: Mercaldi GF]]
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[[Category: G6pd]]
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[[Category: G6pdh]]
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[[Category: Oxidoreductase]]
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[[Category: Pentose phosphate pathway]]
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[[Category: Redox balance]]
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Current revision

Trypanosoma cruzi Glucose-6-phosphate Dehydrogenase in complex with G6P and NADPH

PDB ID 5aq1

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