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5d6r

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==Acetolactate Synthase from Klebsiella pneumoniae in Complex with Mechanism-Based Inhibitor==
==Acetolactate Synthase from Klebsiella pneumoniae in Complex with Mechanism-Based Inhibitor==
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<StructureSection load='5d6r' size='340' side='right' caption='[[5d6r]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
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<StructureSection load='5d6r' size='340' side='right'caption='[[5d6r]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5d6r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D6R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D6R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5d6r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D6R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EN0:3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-[(Z)-2-FLUORO-1-HYDROXY-2-PHOSPHONOETHENYL]-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM'>EN0</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.276&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EN0:3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-[(Z)-2-FLUORO-1-HYDROXY-2-PHOSPHONOETHENYL]-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM'>EN0</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d6r OCA], [http://pdbe.org/5d6r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d6r RCSB], [http://www.ebi.ac.uk/pdbsum/5d6r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d6r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d6r OCA], [https://pdbe.org/5d6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d6r RCSB], [https://www.ebi.ac.uk/pdbsum/5d6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d6r ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ILVB_KLEPN ILVB_KLEPN]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acetolactate synthase]]
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[[Category: Klebsiella pneumoniae]]
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[[Category: Andrews, F H]]
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[[Category: Large Structures]]
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[[Category: Latta, A J]]
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[[Category: Andrews FH]]
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[[Category: McLeish, M J]]
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[[Category: Latta AJ]]
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[[Category: Inhibition intermediate synthase]]
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[[Category: McLeish MJ]]
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[[Category: Transferase]]
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Current revision

Acetolactate Synthase from Klebsiella pneumoniae in Complex with Mechanism-Based Inhibitor

PDB ID 5d6r

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