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4y16

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==Crystal structure of the mCD1d/NC-aGC/iNKTCR ternary complex==
==Crystal structure of the mCD1d/NC-aGC/iNKTCR ternary complex==
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<StructureSection load='4y16' size='340' side='right' caption='[[4y16]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='4y16' size='340' side='right'caption='[[4y16]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4y16]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y16 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Y16 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4y16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y16 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=48G:N-[(2S,3S,4R)-3,4-DIHYDROXY-1-{[6-O-(NAPHTHALEN-1-YLCARBAMOYL)-ALPHA-D-GALACTOPYRANOSYL]OXY}OCTADECAN-2-YL]HEXACOSANAMIDE'>48G</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y2d|4y2d]], [[4y4f|4y4f]], [[4y4h|4y4h]], [[4y4k|4y4k]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=48G:N-[(2S,3S,4R)-3,4-DIHYDROXY-1-{[6-O-(NAPHTHALEN-1-YLCARBAMOYL)-ALPHA-D-GALACTOPYRANOSYL]OXY}OCTADECAN-2-YL]HEXACOSANAMIDE'>48G</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4y16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y16 OCA], [http://pdbe.org/4y16 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4y16 RCSB], [http://www.ebi.ac.uk/pdbsum/4y16 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4y16 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y16 OCA], [https://pdbe.org/4y16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y16 RCSB], [https://www.ebi.ac.uk/pdbsum/4y16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y16 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE]] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref> [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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[https://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[T-cell receptor|T-cell receptor]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[CD1|CD1]]
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*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Nemcovic, M]]
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[[Category: Homo sapiens]]
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[[Category: Zajonc, D M]]
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[[Category: Large Structures]]
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[[Category: Glycolipid antigen presentation]]
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[[Category: Mus musculus]]
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[[Category: Ig-fold]]
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[[Category: Nemcovic M]]
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[[Category: Immune system]]
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[[Category: Zajonc DM]]
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[[Category: Mhc-fold]]
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[[Category: T cell receptor]]
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Current revision

Crystal structure of the mCD1d/NC-aGC/iNKTCR ternary complex

PDB ID 4y16

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