1kaw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:45, 7 February 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1kaw.jpg|left|200px]]
 
-
{{Structure
+
==STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)==
-
|PDB= 1kaw |SIZE=350|CAPTION= <scene name='initialview01'>1kaw</scene>, resolution 2.9&Aring;
+
<StructureSection load='1kaw' size='340' side='right'caption='[[1kaw]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[1kaw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KAW FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
|GENE=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kaw OCA], [https://pdbe.org/1kaw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kaw RCSB], [https://www.ebi.ac.uk/pdbsum/1kaw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kaw ProSAT]</span></td></tr>
-
|DOMAIN=
+
</table>
-
|RELATEDENTRY=
+
== Function ==
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kaw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kaw OCA], [http://www.ebi.ac.uk/pdbsum/1kaw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1kaw RCSB]</span>
+
[https://www.uniprot.org/uniprot/SSB_ECOLI SSB_ECOLI] This protein is essential for replication of the chromosomes and its single-stranded DNA phages. It is also involved in DNA recombination and repair.
-
}}
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/1kaw_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kaw ConSurf].
 +
<div style="clear:both"></div>
-
'''STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)'''
+
==See Also==
-
 
+
*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
-
 
+
__TOC__
-
==Overview==
+
</StructureSection>
-
The crystal structure of the tetrameric DNA-binding domain of the single-stranded DNA binding protein from Escherichia coli was determined at a resolution of 2.9 A using multiwavelength anomalous dispersion. Each monomer in the tetramer is topologically similar to an oligomer-binding fold. Two monomers each contribute three beta-strands to a single six-stranded beta-sheet to form a dimer. Two dimer-dimer interfaces are observed within the crystal. One of these stabilizes the tetramer in solution. The other interface promotes a superhelical structure within the crystal that may reflect tetramer-tetramer interactions involved in the positive cooperative binding of the single-stranded DNA-binding protein to single-stranded DNA.
+
-
 
+
-
==About this Structure==
+
-
1KAW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAW OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of the homo-tetrameric DNA binding domain of Escherichia coli single-stranded DNA-binding protein determined by multiwavelength x-ray diffraction on the selenomethionyl protein at 2.9-A resolution., Raghunathan S, Ricard CS, Lohman TM, Waksman G, Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6652-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9192620 9192620]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Raghunathan, S.]]
+
[[Category: Raghunathan S]]
-
[[Category: Waksman, G.]]
+
[[Category: Waksman G]]
-
[[Category: dna-binding protein]]
+
-
[[Category: single stranded dna binding protein]]
+
-
[[Category: ssb]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:45:53 2008''
+

Current revision

STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)

PDB ID 1kaw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1kaw"
Personal tools