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5ktm

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==Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with a bound Fe4S4 cluster==
==Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with a bound Fe4S4 cluster==
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<StructureSection load='5ktm' size='340' side='right' caption='[[5ktm]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
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<StructureSection load='5ktm' size='340' side='right'caption='[[5ktm]], [[Resolution|resolution]] 1.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ktm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KTM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ktm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KTM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.44&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kts|5kts]], [[5ktt|5ktt]], [[5ktr|5ktr]], [[5kto|5kto]], [[5ktn|5ktn]], [[5ktp|5ktp]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quinolinate_synthase Quinolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.72 2.5.1.72] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ktm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ktm OCA], [https://pdbe.org/5ktm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ktm RCSB], [https://www.ebi.ac.uk/pdbsum/5ktm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ktm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ktm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ktm OCA], [http://pdbe.org/5ktm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ktm RCSB], [http://www.ebi.ac.uk/pdbsum/5ktm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ktm ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NADA_PYRHO NADA_PYRHO]] Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity).
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[https://www.uniprot.org/uniprot/NADA_PYRHO NADA_PYRHO] Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Quinolinate synthase]]
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[[Category: Large Structures]]
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[[Category: Ealick, S E]]
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[[Category: Pyrococcus horikoshii OT3]]
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[[Category: Fenwick, M K]]
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[[Category: Ealick SE]]
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[[Category: Biosynthetic enzyme]]
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[[Category: Fenwick MK]]
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[[Category: Dehydratase]]
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[[Category: Holoenzyme]]
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[[Category: Iron-sulfur cluster]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with a bound Fe4S4 cluster

PDB ID 5ktm

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