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5ev0

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==Crystal structure of ragweed profilin Amb a 8 in complex with poly-Pro14==
==Crystal structure of ragweed profilin Amb a 8 in complex with poly-Pro14==
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<StructureSection load='5ev0' size='340' side='right' caption='[[5ev0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='5ev0' size='340' side='right'caption='[[5ev0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ev0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EV0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EV0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ev0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ambrosia_artemisiifolia Ambrosia artemisiifolia] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EV0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EV0 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ev0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ev0 OCA], [http://pdbe.org/5ev0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ev0 RCSB], [http://www.ebi.ac.uk/pdbsum/5ev0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ev0 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ev0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ev0 OCA], [https://pdbe.org/5ev0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ev0 RCSB], [https://www.ebi.ac.uk/pdbsum/5ev0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ev0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q2KN24_AMBAR Q2KN24_AMBAR]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.[RuleBase:RU003908]
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[https://www.uniprot.org/uniprot/Q2KN24_AMBAR Q2KN24_AMBAR] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.[RuleBase:RU003908]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ev0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ev0" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Profilin 3D Structures|Profilin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chruszcz, M]]
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[[Category: Ambrosia artemisiifolia]]
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[[Category: He, J Z]]
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[[Category: Large Structures]]
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[[Category: Offermann, L R]]
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[[Category: Synthetic construct]]
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[[Category: Perdue, M L]]
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[[Category: Chruszcz M]]
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[[Category: Allergen]]
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[[Category: He JZ]]
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[[Category: Offermann LR]]
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[[Category: Perdue ML]]

Current revision

Crystal structure of ragweed profilin Amb a 8 in complex with poly-Pro14

PDB ID 5ev0

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