5gnv
From Proteopedia
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(New page: '''Unreleased structure''' The entry 5gnv is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain== | |
| + | <StructureSection load='5gnv' size='340' side='right'caption='[[5gnv]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5gnv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GNV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.596Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gnv OCA], [https://pdbe.org/5gnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gnv RCSB], [https://www.ebi.ac.uk/pdbsum/5gnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gnv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DLG4_RAT DLG4_RAT] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.<ref>PMID:15317815</ref> <ref>PMID:15358863</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Postsynaptic density protein 3D structures|Postsynaptic density protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Shang Y]] | ||
| + | [[Category: Xia Y]] | ||
| + | [[Category: Zhu J]] | ||
| + | [[Category: Zhu R]] | ||
Current revision
Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain
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Categories: Large Structures | Mus musculus | Rattus norvegicus | Shang Y | Xia Y | Zhu J | Zhu R
