5gon

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m (Protected "5gon" [edit=sysop:move=sysop])
Current revision (09:13, 20 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5gon is ON HOLD
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==Structures of a beta-lactam bridged analogue in complex with tubulin==
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<StructureSection load='5gon' size='340' side='right'caption='[[5gon]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5gon]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GON FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6ZR:(3R,4R)-4-(4-METHOXY-3-OXIDANYL-PHENYL)-3-METHYL-1-(3,4,5-TRIMETHOXYPHENYL)AZETIDIN-2-ONE'>6ZR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gon OCA], [https://pdbe.org/5gon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gon RCSB], [https://www.ebi.ac.uk/pdbsum/5gon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gon ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
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Authors: Lu Zhou, Yan Liu, Cheng Luo, Yang Wang
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==See Also==
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*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
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Description: Structures of a beta-lactam bridged analogue in complex with tubulin
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*[[Tubulin 3D Structures|Tubulin 3D Structures]]
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[[Category: Unreleased Structures]]
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*[[Tubulin tyrosine ligase 3D structures|Tubulin tyrosine ligase 3D structures]]
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[[Category: Lu Zhou, Yan Liu, Cheng Luo, Yang Wang]]
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__TOC__
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</StructureSection>
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[[Category: Bos taurus]]
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[[Category: Gallus gallus]]
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[[Category: Large Structures]]
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[[Category: Rattus norvegicus]]
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[[Category: Cheng L]]
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[[Category: Liu Y]]
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[[Category: Wang Y]]
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[[Category: Zhou L]]

Current revision

Structures of a beta-lactam bridged analogue in complex with tubulin

PDB ID 5gon

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