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3qz1

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==Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)==
==Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)==
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<StructureSection load='3qz1' size='340' side='right' caption='[[3qz1]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='3qz1' size='340' side='right'caption='[[3qz1]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qz1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QZ1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qz1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QZ1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3QZ:(9BETA)-17-HYDROXYPREGN-4-ENE-3,20-DIONE'>3QZ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYP21, CYP21A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 BOVIN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3QZ:(9BETA)-17-HYDROXYPREGN-4-ENE-3,20-DIONE'>3QZ</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Steroid_21-monooxygenase Steroid 21-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.10 1.14.99.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qz1 OCA], [https://pdbe.org/3qz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qz1 RCSB], [https://www.ebi.ac.uk/pdbsum/3qz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qz1 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qz1 OCA], [http://pdbe.org/3qz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qz1 RCSB], [http://www.ebi.ac.uk/pdbsum/3qz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qz1 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CP21A_BOVIN CP21A_BOVIN]] Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
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[https://www.uniprot.org/uniprot/CP21A_BOVIN CP21A_BOVIN] Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bovin]]
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[[Category: Bos taurus]]
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[[Category: Steroid 21-monooxygenase]]
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[[Category: Large Structures]]
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[[Category: Waterman, M R]]
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[[Category: Waterman MR]]
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[[Category: Zhao, B]]
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[[Category: Zhao B]]
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[[Category: 21-hydroxylase]]
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[[Category: Oxidoreductase]]
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[[Category: P450 monooxygenase]]
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Current revision

Crystal Structure of Bovine Steroid of 21-hydroxylase (P450c21)

PDB ID 3qz1

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