4gmd
From Proteopedia
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| ==The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate== | ==The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate== | ||
| - | <StructureSection load='4gmd' size='340' side='right' caption='[[4gmd]], [[Resolution|resolution]] 1.98Å' scene=''> | + | <StructureSection load='4gmd' size='340' side='right'caption='[[4gmd]], [[Resolution|resolution]] 1.98Å' scene=''> | 
| == Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gmd]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4gmd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GMD FirstGlance]. <br> | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.98Å</td></tr> | 
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATM:3-AZIDO-3-DEOXYTHYMIDINE-5-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmd OCA], [https://pdbe.org/4gmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gmd RCSB], [https://www.ebi.ac.uk/pdbsum/4gmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gmd ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
| </table> | </table> | ||
| == Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/KTHY_PSEAE KTHY_PSEAE] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity). | 
| ==See Also== | ==See Also== | ||
| - | *[[Thymidylate kinase|Thymidylate kinase]] | + | *[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]] | 
| __TOC__ | __TOC__ | ||
| </StructureSection> | </StructureSection> | ||
| - | [[Category:  | + | [[Category: Large Structures]] | 
| - | [[Category:  | + | [[Category: Pseudomonas aeruginosa PAO1]] | 
| - | [[Category: Jedrzejczak | + | [[Category: Jedrzejczak R]] | 
| - | [[Category: Joachimiak | + | [[Category: Joachimiak A]] | 
| - | [[Category: Joachimiak | + | [[Category: Joachimiak G]] | 
| - | + | [[Category: Sacchettini J]] | |
| - | + | [[Category: Tan K]] | |
| - | [[Category: Sacchettini | + | |
| - | [[Category: Tan | + | |
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Current revision
The crystal structure of thymidylate kinase from Pseudomonas aeruginosa PAO1 in complex with AZT Monophosphate
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