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2yf0
From Proteopedia
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| - | == | + | ==Human Myotubularin related protein 6 (MTMR6)== |
| - | <StructureSection load='2yf0' size='340' side='right' caption='[[2yf0]], [[Resolution|resolution]] 2.65Å' scene=''> | + | <StructureSection load='2yf0' size='340' side='right'caption='[[2yf0]], [[Resolution|resolution]] 2.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yf0]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2yf0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YF0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YF0 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yf0 OCA], [https://pdbe.org/2yf0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yf0 RCSB], [https://www.ebi.ac.uk/pdbsum/2yf0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yf0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MTMR6_HUMAN MTMR6_HUMAN] Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.<ref>PMID:15831468</ref> <ref>PMID:16847315</ref> |
==See Also== | ==See Also== | ||
| - | *[[Dual specificity phosphatase|Dual specificity phosphatase]] | + | *[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Berglund | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Berglund H]] |
| - | [[Category: Collins | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Collins R]] |
| - | [[Category: Flodin | + | [[Category: Edwards AM]] |
| - | [[Category: Flores | + | [[Category: Flodin S]] |
| - | [[Category: Graslund | + | [[Category: Flores A]] |
| - | [[Category: Hammarstrom | + | [[Category: Graslund S]] |
| - | [[Category: Johansson | + | [[Category: Hammarstrom M]] |
| - | [[Category: Karlberg | + | [[Category: Johansson I]] |
| - | [[Category: Kotenyova | + | [[Category: Karlberg T]] |
| - | [[Category: Kouznetsova | + | [[Category: Kotenyova T]] |
| - | [[Category: Moche | + | [[Category: Kouznetsova E]] |
| - | [[Category: Nordlund | + | [[Category: Moche M]] |
| - | [[Category: Nyman | + | [[Category: Nordlund P]] |
| - | [[Category: Persson | + | [[Category: Nyman T]] |
| - | [[Category: Schuler | + | [[Category: Persson C]] |
| - | [[Category: Schutz | + | [[Category: Schuler H]] |
| - | [[Category: Siponen | + | [[Category: Schutz P]] |
| - | [[Category: Thorsell | + | [[Category: Siponen MI]] |
| - | [[Category: Tresaugues | + | [[Category: Thorsell AG]] |
| - | [[Category: | + | [[Category: Tresaugues L]] |
| - | [[Category: Wahlberg | + | [[Category: VanDenBerg S]] |
| - | [[Category: Weigelt | + | [[Category: Wahlberg E]] |
| - | [[Category: Welin | + | [[Category: Weigelt J]] |
| - | + | [[Category: Welin M]] | |
Current revision
Human Myotubularin related protein 6 (MTMR6)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berglund H | Bountra C | Collins R | Edwards AM | Flodin S | Flores A | Graslund S | Hammarstrom M | Johansson I | Karlberg T | Kotenyova T | Kouznetsova E | Moche M | Nordlund P | Nyman T | Persson C | Schuler H | Schutz P | Siponen MI | Thorsell AG | Tresaugues L | VanDenBerg S | Wahlberg E | Weigelt J | Welin M
