This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3pwh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:08, 1 November 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Thermostabilised Adenosine A2A Receptor==
==Thermostabilised Adenosine A2A Receptor==
-
<StructureSection load='3pwh' size='340' side='right' caption='[[3pwh]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
+
<StructureSection load='3pwh' size='340' side='right'caption='[[3pwh]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3pwh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PWH FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3pwh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PWH FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.296&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwh OCA], [http://pdbe.org/3pwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pwh RCSB], [http://www.ebi.ac.uk/pdbsum/3pwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwh ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwh OCA], [https://pdbe.org/3pwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pwh RCSB], [https://www.ebi.ac.uk/pdbsum/3pwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
+
[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 21:
==See Also==
==See Also==
-
*[[Adenosine A2A receptor|Adenosine A2A receptor]]
+
*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]]
-
*[[G protein-coupled receptor|G protein-coupled receptor]]
+
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Dore, A S]]
+
[[Category: Large Structures]]
-
[[Category: Errey, J C]]
+
[[Category: Dore AS]]
-
[[Category: Hurrell, E]]
+
[[Category: Errey JC]]
-
[[Category: Magnani, F]]
+
[[Category: Hurrell E]]
-
[[Category: Marshall, F H]]
+
[[Category: Magnani F]]
-
[[Category: Ng, I]]
+
[[Category: Marshall FH]]
-
[[Category: Robertson, N]]
+
[[Category: Ng I]]
-
[[Category: Tate, C G]]
+
[[Category: Robertson N]]
-
[[Category: Tehan, B]]
+
[[Category: Tate CG]]
-
[[Category: Weir, M]]
+
[[Category: Tehan B]]
-
[[Category: G-protein]]
+
[[Category: Weir M]]
-
[[Category: Gpcr]]
+
-
[[Category: Inverse agonist]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Signaling protein]]
+

Current revision

Thermostabilised Adenosine A2A Receptor

PDB ID 3pwh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3pwh"
Personal tools