4fn8

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==Crystal structure of the Mtb enoyl CoA isomerase (Rv0632c)in complex with acetoacetyl CoA==
==Crystal structure of the Mtb enoyl CoA isomerase (Rv0632c)in complex with acetoacetyl CoA==
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<StructureSection load='4fn8' size='340' side='right' caption='[[4fn8]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
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<StructureSection load='4fn8' size='340' side='right'caption='[[4fn8]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fn8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FN8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FN8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fn8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FN8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FN8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.831&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fn7|4fn7]], [[4fnb|4fnb]], [[4fnd|4fnd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">echA3, MT0660, Rv0632c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fn8 OCA], [https://pdbe.org/4fn8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fn8 RCSB], [https://www.ebi.ac.uk/pdbsum/4fn8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fn8 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-CoA_hydratase Enoyl-CoA hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.17 4.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fn8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fn8 OCA], [http://pdbe.org/4fn8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fn8 RCSB], [http://www.ebi.ac.uk/pdbsum/4fn8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fn8 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P96907_MYCTX P96907_MYCTX]
==See Also==
==See Also==
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*[[Enoyl-CoA hydratase|Enoyl-CoA hydratase]]
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*[[Enoyl-CoA hydratase 3D structures|Enoyl-CoA hydratase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enoyl-CoA hydratase]]
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[[Category: Large Structures]]
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[[Category: Bruning, J B]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Dang, N]]
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[[Category: Bruning JB]]
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[[Category: Gao, N]]
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[[Category: Dang N]]
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[[Category: Hernandez, E D]]
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[[Category: Gao N]]
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[[Category: Hung, L W]]
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[[Category: Hernandez ED]]
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[[Category: Li, H]]
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[[Category: Hung LW]]
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[[Category: Sacchettini, J C]]
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[[Category: Li H]]
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[[Category: Structural genomic]]
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[[Category: Sacchettini JC]]
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[[Category: Crotonase superfamily]]
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[[Category: Isomerase]]
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[[Category: Tbsgc]]
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Current revision

Crystal structure of the Mtb enoyl CoA isomerase (Rv0632c)in complex with acetoacetyl CoA

PDB ID 4fn8

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