This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4m4g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:55, 20 March 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, N-acetylserine.==
==Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, N-acetylserine.==
-
<StructureSection load='4m4g' size='340' side='right' caption='[[4m4g]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+
<StructureSection load='4m4g' size='340' side='right'caption='[[4m4g]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4m4g]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M4G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M4G FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4m4g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M4G FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SAC:N-ACETYL-SERINE'>SAC</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gwo|4gwo]], [[4gxa|4gxa]], [[4lon|4lon]], [[4lp2|4lp2]], [[4lq2|4lq2]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SAC:N-ACETYL-SERINE'>SAC</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m4g OCA], [http://pdbe.org/4m4g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4m4g RCSB], [http://www.ebi.ac.uk/pdbsum/4m4g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4m4g ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m4g OCA], [https://pdbe.org/4m4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m4g RCSB], [https://www.ebi.ac.uk/pdbsum/4m4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m4g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CYSB_SALTY CYSB_SALTY]] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
+
[https://www.uniprot.org/uniprot/CYSB_SALTY CYSB_SALTY] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.
==See Also==
==See Also==
-
*[[Transcriptional activator|Transcriptional activator]]
+
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Kumaran, S]]
+
[[Category: Large Structures]]
-
[[Category: Mittal, M]]
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-
[[Category: Singh, A K]]
+
[[Category: Kumaran S]]
-
[[Category: Cytoplasmic]]
+
[[Category: Mittal M]]
-
[[Category: Dna binding]]
+
[[Category: Singh AK]]
-
[[Category: Gene regulation]]
+
-
[[Category: Lttr]]
+
-
[[Category: N-acetyl serine binding]]
+
-
[[Category: O-acetyl serine]]
+
-
[[Category: Rossmann fold]]
+
-
[[Category: Transcriptional regulation]]
+
-
[[Category: Whth motif/ pbp type ii alpha/beta fold]]
+

Current revision

Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium LT2 in complex with effector ligand, N-acetylserine.

PDB ID 4m4g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools