4ak4

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==High resolution structure of Galactose Binding lectin from Champedak (CGB)==
==High resolution structure of Galactose Binding lectin from Champedak (CGB)==
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<StructureSection load='4ak4' size='340' side='right' caption='[[4ak4]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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<StructureSection load='4ak4' size='340' side='right'caption='[[4ak4]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ak4]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AK4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AK4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ak4]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AK4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4akb|4akb]], [[4akc|4akc]], [[4akd|4akd]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ak4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ak4 OCA], [http://pdbe.org/4ak4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ak4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ak4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ak4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ak4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ak4 OCA], [https://pdbe.org/4ak4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ak4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ak4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ak4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. [[http://www.uniprot.org/uniprot/LECB4_ARTIN LECB4_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum (By similarity).
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[https://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4ak4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4ak4" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Agglutinin 3D structures|Agglutinin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Artocarpus integer]]
[[Category: Artocarpus integer]]
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[[Category: Abdul-Rahman, P S]]
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[[Category: Large Structures]]
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[[Category: Cogdell, R J]]
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[[Category: Abdul-Rahman PS]]
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[[Category: Gabrielsen, M]]
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[[Category: Cogdell RJ]]
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[[Category: Hashim, O H]]
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[[Category: Gabrielsen M]]
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[[Category: Othman, S]]
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[[Category: Hashim OH]]
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[[Category: Lectin]]
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[[Category: Othman S]]
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[[Category: Mannose]]
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[[Category: Plant]]
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[[Category: Sugar binding protein]]
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Current revision

High resolution structure of Galactose Binding lectin from Champedak (CGB)

PDB ID 4ak4

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