This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4bjr
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the complex between Prokaryotic Ubiquitin-like Protein Pup and its Ligase PafA== | ==Crystal structure of the complex between Prokaryotic Ubiquitin-like Protein Pup and its Ligase PafA== | ||
| - | <StructureSection load='4bjr' size='340' side='right' caption='[[4bjr]], [[Resolution|resolution]] 2.80Å' scene=''> | + | <StructureSection load='4bjr' size='340' side='right'caption='[[4bjr]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bjr]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4bjr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum Corynebacterium glutamicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BJR FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bjr OCA], [https://pdbe.org/4bjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bjr RCSB], [https://www.ebi.ac.uk/pdbsum/4bjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bjr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PUP_CORGL PUP_CORGL] Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.[HAMAP-Rule:MF_02106]<ref>PMID:22910360</ref> [https://www.uniprot.org/uniprot/PAFA_CORGL PAFA_CORGL] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Corynebacterium glutamicum]] |
| - | [[Category: Ban | + | [[Category: Large Structures]] |
| - | [[Category: Barandun | + | [[Category: Ban N]] |
| - | [[Category: Delley | + | [[Category: Barandun J]] |
| - | [[Category: Weber-Ban | + | [[Category: Delley CL]] |
| - | + | [[Category: Weber-Ban E]] | |
| - | + | ||
Current revision
Crystal structure of the complex between Prokaryotic Ubiquitin-like Protein Pup and its Ligase PafA
| |||||||||||
