3m84

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==Crystal Structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis==
==Crystal Structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis==
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<StructureSection load='3m84' size='340' side='right' caption='[[3m84]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='3m84' size='340' side='right'caption='[[3m84]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3m84]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fratt Fratt]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M84 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M84 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3m84]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Francisella_tularensis_subsp._tularensis_SCHU_S4 Francisella tularensis subsp. tularensis SCHU S4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M84 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M84 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.699&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">purM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=177416 FRATT])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m84 OCA], [https://pdbe.org/3m84 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m84 RCSB], [https://www.ebi.ac.uk/pdbsum/3m84 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m84 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m84 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m84 OCA], [http://pdbe.org/3m84 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m84 RCSB], [http://www.ebi.ac.uk/pdbsum/3m84 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m84 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5NGF2_FRATT Q5NGF2_FRATT]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m8/3m84_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m8/3m84_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fratt]]
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[[Category: Francisella tularensis subsp. tularensis SCHU S4]]
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[[Category: Anderson, W F]]
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[[Category: Large Structures]]
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[[Category: Hasseman, J]]
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[[Category: Anderson WF]]
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[[Category: Joachimiak, A]]
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[[Category: Hasseman J]]
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[[Category: Kim, Y]]
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[[Category: Joachimiak A]]
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[[Category: Maltseva, N]]
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[[Category: Kim Y]]
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[[Category: Alpha-beta fold]]
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[[Category: Maltseva N]]
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[[Category: Atp-binding]]
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[[Category: Structural genomic]]
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[[Category: Csgid]]
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[[Category: Ligase]]
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[[Category: Nucleotide-binding]]
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[[Category: Purine biosynthesis]]
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Current revision

Crystal Structure of Phosphoribosylaminoimidazole Synthetase from Francisella tularensis

PDB ID 3m84

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