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4f37

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==Structure of the tethered N-terminus of Alzheimer's disease A peptide==
==Structure of the tethered N-terminus of Alzheimer's disease A peptide==
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<StructureSection load='4f37' size='340' side='right' caption='[[4f37]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
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<StructureSection load='4f37' size='340' side='right'caption='[[4f37]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4f37]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F37 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F37 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4f37]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F37 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bkj|3bkj]], [[1ayi|1ayi]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f37 OCA], [https://pdbe.org/4f37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f37 RCSB], [https://www.ebi.ac.uk/pdbsum/4f37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f37 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f37 OCA], [http://pdbe.org/4f37 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f37 RCSB], [http://www.ebi.ac.uk/pdbsum/4f37 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f37 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX]] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
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[https://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Colicin Immunity Protein|Colicin Immunity Protein]]
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*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
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*[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Caine, J M]]
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[[Category: Mus musculus]]
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[[Category: Davydova, N]]
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[[Category: Caine JM]]
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[[Category: Hittaki, M]]
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[[Category: Davydova N]]
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[[Category: Masters, C L]]
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[[Category: Hittaki M]]
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[[Category: Nisbet, R M]]
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[[Category: Masters CL]]
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[[Category: Nuttall, S D]]
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[[Category: Nisbet RM]]
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[[Category: Pearce, L A]]
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[[Category: Nuttall SD]]
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[[Category: Rober, R]]
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[[Category: Pearce LA]]
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[[Category: Streltsov, V A]]
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[[Category: Rober R]]
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[[Category: Varghese, J N]]
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[[Category: Streltsov VA]]
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[[Category: Alzheimer's disease]]
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[[Category: Varghese JN]]
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[[Category: Amyloid-beta]]
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[[Category: Immune system]]
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Current revision

Structure of the tethered N-terminus of Alzheimer's disease A peptide

PDB ID 4f37

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