3olj

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==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2)==
==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2)==
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<StructureSection load='3olj' size='340' side='right' caption='[[3olj]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3olj' size='340' side='right'caption='[[3olj]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3olj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OLJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3olj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OLJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RRM2, RR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3olj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3olj OCA], [https://pdbe.org/3olj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3olj RCSB], [https://www.ebi.ac.uk/pdbsum/3olj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3olj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3olj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3olj OCA], [http://pdbe.org/3olj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3olj RCSB], [http://www.ebi.ac.uk/pdbsum/3olj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3olj ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
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[https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
==See Also==
==See Also==
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*[[Ribonucleotide reductase|Ribonucleotide reductase]]
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Large Structures]]
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[[Category: Chen, B E]]
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[[Category: Chen BE]]
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[[Category: Chen, X H]]
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[[Category: Chen XH]]
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[[Category: Jiang, H J]]
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[[Category: Jiang HJ]]
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[[Category: Shao, J M]]
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[[Category: Shao JM]]
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[[Category: Xu, Z J]]
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[[Category: Xu ZJ]]
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[[Category: Yang, C G]]
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[[Category: Yang CG]]
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[[Category: Zhu, W L]]
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[[Category: Zhu WL]]
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[[Category: Hrrm2]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2)

PDB ID 3olj

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