4fqs

<StructureSection load='4fqs' size='340' side='right'caption='[[4fqs]], [[Resolution|resolution]] 1.80&Aring;' scene=''>

<table><tr><td colspan='2'>[[4fqs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FQS FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LYA:2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC+ACID'>LYA</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqs OCA], [https://pdbe.org/4fqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fqs RCSB], [https://www.ebi.ac.uk/pdbsum/4fqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fqs ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/TYSY_MYCTU TYSY_MYCTU] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).

*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]

[[Category: Large Structures]]

[[Category: Mycobacterium tuberculosis H37Rv]]

[[Category: Bruning JB]]

[[Category: Harshbarger W]]

[[Category: Reddy MCM]]

[[Category: Sacchettini JC]]