3gyz

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==Crystal structure of IpgC from Shigella flexneri==
==Crystal structure of IpgC from Shigella flexneri==
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<StructureSection load='3gyz' size='340' side='right' caption='[[3gyz]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<StructureSection load='3gyz' size='340' side='right'caption='[[3gyz]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3gyz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GYZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GYZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gz1|3gz1]], [[3gz2|3gz2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ipgC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [https://pdbe.org/3gyz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [https://www.ebi.ac.uk/pdbsum/3gyz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gyz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gyz OCA], [http://pdbe.org/3gyz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gyz RCSB], [http://www.ebi.ac.uk/pdbsum/3gyz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gyz ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL]] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.
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[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/3gyz_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gy/3gyz_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Shigella paradysenteriae weldin 1927]]
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[[Category: Large Structures]]
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[[Category: Kolbe, M]]
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[[Category: Shigella flexneri]]
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[[Category: Lokareddy, R K]]
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[[Category: Kolbe M]]
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[[Category: Lunelli, M]]
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[[Category: Lokareddy RK]]
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[[Category: Zychlinsky, A]]
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[[Category: Lunelli M]]
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[[Category: Asymmetric homodimer]]
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[[Category: Zychlinsky A]]
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[[Category: Chaperone]]
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[[Category: Tetratricopeptide repeat]]
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[[Category: Tpr]]
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[[Category: Virulence]]
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Current revision

Crystal structure of IpgC from Shigella flexneri

PDB ID 3gyz

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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