3k8n

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==Crystal structure of E. Coli CCMG==
==Crystal structure of E. Coli CCMG==
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<StructureSection load='3k8n' size='340' side='right' caption='[[3k8n]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3k8n' size='340' side='right'caption='[[3k8n]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3k8n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K8N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K8N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3k8n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K8N FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kng|1kng]], [[2b1k|2b1k]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2195, ccmG, dsbE, JW2183, yejQ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k8n OCA], [https://pdbe.org/3k8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k8n RCSB], [https://www.ebi.ac.uk/pdbsum/3k8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k8n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k8n OCA], [http://pdbe.org/3k8n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k8n RCSB], [http://www.ebi.ac.uk/pdbsum/3k8n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k8n ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DSBE_ECOLI DSBE_ECOLI]] Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase. DsbE is maintained in a reduced state by DsbD.
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[https://www.uniprot.org/uniprot/DSBE_ECOLI DSBE_ECOLI] Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase. DsbE is maintained in a reduced state by DsbD.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/3k8n_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/3k8n_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Thiol:disulfide interchange protein|Thiol:disulfide interchange protein]]
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*[[Thiol:disulfide interchange protein 3D structures|Thiol:disulfide interchange protein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: CSMP, Center for Structures of Membrane Proteins]]
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[[Category: Large Structures]]
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[[Category: Newby, Z]]
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[[Category: Newby Z]]
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[[Category: Savage, D]]
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[[Category: Savage D]]
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[[Category: Stroud, R M]]
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[[Category: Stroud RM]]
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[[Category: C-terminal thioredoxin-like domain]]
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[[Category: Cell inner membrane]]
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[[Category: Cell membrane]]
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[[Category: Center for structures of membrane protein]]
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[[Category: Csmp]]
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[[Category: Cytochrome c-type biogenesis]]
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[[Category: Disulfide bond]]
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[[Category: Membrane]]
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[[Category: N-terminal transmembrane helix]]
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[[Category: Oxidoreductase]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Redox-active center]]
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[[Category: Structural genomic]]
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[[Category: Transmembrane]]
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Current revision

Crystal structure of E. Coli CCMG

PDB ID 3k8n

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