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4mgg
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==Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121== | ==Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121== | ||
| - | <StructureSection load='4mgg' size='340' side='right' caption='[[4mgg]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4mgg' size='340' side='right'caption='[[4mgg]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4mgg]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4mgg]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Roseibium_aggregatum_IAM_12614 Roseibium aggregatum IAM 12614]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MGG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MGG FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mgg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mgg OCA], [https://pdbe.org/4mgg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mgg RCSB], [https://www.ebi.ac.uk/pdbsum/4mgg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mgg ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/C3HPD_ROSAI C3HPD_ROSAI] Catalyzes the dehydration of cis-3-hydroxy-L-proline (c3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts c3LHyp to L-proline, which allows L.aggregata to grow on c3LHyp as a sole carbon source. Also catalyzes the epimerization of c3LHyp to trans-3-hydroxy-D-proline (t3DHyp), a competing reaction occurring from the same enolate anion intermediate. L-proline, t3LHyp, t4LHyp, c4DHyp and their methylated derivatives are not substrates.<ref>PMID:25608448</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Enolase 3D structures|Enolase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Roseibium aggregatum IAM 12614]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Bonanno JB]] |
| - | [[Category: | + | [[Category: Gerlt JA]] |
| - | [[Category: | + | [[Category: Morisco LL]] |
| - | [[Category: Sojitra | + | [[Category: Sojitra S]] |
| - | [[Category: Vetting | + | [[Category: Vetting MW]] |
| - | [[Category: Wasserman | + | [[Category: Wasserman SR]] |
| - | [[Category: Zhang | + | [[Category: Zhang X]] |
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Current revision
Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121
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